PARP Quiz! What Are Expert Strategies for Targeting DNA Repair in Prostate Cancer?



Date / Time
Event Details


Goal Statement
The goal of this activity is to improve the knowledge, confidence, and competence of learners to integrate PARP inhibitors into the treatment of men with prostate cancer.

Target Audience 
This program is intended for physicians and other healthcare providers who care for patients with prostate cancer.

Learning Objectives 

  • Describe the rationale and process for assessing germline and somatic DNA repair pathway alterations in prostate cancer including the poor prognosis in the absence of targeted treatment
  • Examine the mechanism of PARP inhibition to achieve “synthetic lethality” in prostate cancer with deficient DNA damage response
  • Interpret test results for predictive markers of PARP inhibitor benefit following evaluation of the available clinical evidence in CRPC harboring BRCA1/2 or other DNA damage response mutations
  • Select PARP inhibitor treatment for appropriate men with prostate cancer
  • Manage adverse events and other barriers to adherence from PARP inhibitors
  • Identify patients suitable for enrollment on ongoing clinical studies investigating PARP inhibitor monotherapy or in combination with other agents in prostate cancer


Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Credit Designation
CCO designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Conflicts of Interest
Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any relevant conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.