A Walk in the PARP: Therapeutic Strategies Targeting DNA Repair Defects in Prostate Cancer

Pre-registration is now closed. We welcome you to register on-site by coming to McCormick Place West, Skyline Ballroom, W375b (Level 3). Remember to bring your AUA badge to expedite your registration.


Join us for this dynamic, CME-certified symposium where an expert panel led by Charles J. Ryan, MD, will review the evolving role of PARP inhibitors in prostate cancer, including an overview of DNA repair deficiencies in prostate cancer, guidance on genetic testing, an update on the latest clinical data on PARP inhibitors for the treatment of prostate cancer and future directions, and case discussions of where PARP inhibitors fit into the standard of care setting.

Sign up now! Registration is complimentary.


Pre-registration is now closed. We welcome you to register on-site by coming to McCormick Place West, Skyline Ballroom, W375b (Level 3). Remember to bring your AUA badge to expedite your registration.

5:30 PM Registration and Dinner

6:00 PM Welcome and IntroductionCharles J. Ryan, MD

6:10 PM Practical Guidance on the Clinical Role of BRCA and Other DNA Damage Repair Genes in Prostate CancerDavid A. Quigley, PhD

6:40 PM Genetic Testing in Prostate Cancer for the Clinician Todd M. Morgan, MD

7:10 PM Targeting DNA Repair Defects in Prostate Cancer: The Role of PARP InhibitorsCharles J. Ryan, MD

7:40 PM Applying the Data to Practice: Panel Discussion of Cases and Audience Question and Answer Session


Date / Time
Event Details


Program Director
Charles Ryan, MD

Professor of Medicine
B.J. Kennedy Chair in Clinical Medical Oncology
 Division of Hematology, Oncology and Transplantation
Department of Medicine
University of Minnesota
Division of Hematology, Oncology and Transplantation
University of Minnesota Health Clinics and Surgery Center
Minneapolis, Minnesota

Todd Morgan, MD

Associate Professor
Department of Urology
University of Michigan
Ann Arbor, Michigan

David Quigley, PhD/ND/EdD

Assistant Adjunct Professor
Department of Epidemiology and Biostatistics
Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco
San Francisco, California

Goal Statement
The goal of this activity is to improve participants’ knowledge of, confidence in, and competence in integrating PARP inhibitors into the treatment of patients with prostate cancer.

Target Audience 
This program is intended for oncologists and urologists and other healthcare providers who care for patients with prostate cancer.

Learning Objectives 

  • Describe the rationale and process for assessing germline and somatic DNA repair pathway alterations in prostate cancer
  • Examine the mechanism of PARP inhibition to achieve “synthetic lethality” in prostate cancer with deficient DNA damage response
  • Evaluate the available clinical evidence for the use of PARP inhibitors to treat metastatic CRPC harboring BRCA1/2 or other DNA damage response mutations
  • Identify patients suitable for enrollment on ongoing clinical studies investigating PARP inhibitor monotherapy or in combination with other agents in prostate cancer


Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Designation of Credit

Physician Continuing Education
CCO designates this live activity for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Conflicts of Interest
Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.